PRODUCT DESCRIPTION
Ivermectin Injection is a ready-to-use, sterile, non-aqueous solution of Ivermectin, which is derived from the avermectins, a family of highly active, broad spectrum, antiparasitic agents which are isolated from fermentation of the soil organism Streptomyces avermitilis.
1% Ivermectin Injection is a 1.0% w/v sterile solution of Ivermection. At the rate of 1ml per 50kg bodyweight by subcutaneous injection, this formulation will deliver the recommended dosage level of 200mcg Ivermectin per kg bodyweight.
PRODUCT INDICATIONS
Ivermectin Injection is indicated for the treatment and control of the following species of gastro-intestinal roundworms, lungworms, eyeworms, warbies, mites and sucking lice.
Gastrointestinal roundworms (adults and fourth stage larvae):
Ostertagia ostertagi (including inhibited larval stages), Ostertagia lyrata, Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia oncophora, Cooperia punctata, Cooperia pectinata, Bunostomum phlebotomum, Oesophagostomum radiatum, Strongyloides papillosus (adult), Nematodirus helvetianus (adult), Nemotodirus spathiger (adult) and Trichuris spp (adult).
Lungworms (adult and fourth stage larvae):
Dictyocaulus Viviparus
Eyeworms
Thelazia spp
Hypoderma bovis and Hypoderma lineatum
Mange Mites
Psoroptes bovis, Sarcoptes scabei var bovis
Sucking lice
Linognathus vituli, Haematopinus eurytemus, and Solenopotes capillatus
Ivermectin Injection may also be used as an aid in the control of the biting louse Damalinia bovis and the mange mite Chorioptes bovis, but complete elimination may not occur.
DOSAGE AND ADMINISTRATION
Ivermectin 1% should be given only by subcutaneous injection at the recommended dosage level of 200mcg ivermectin per kilogram bodyweight. Each ml contains 10 mg of ivermectin sufficient to treat 50kg of bodyweight. Use the following dosage schedule.
Bodywt (kg) Dose Vol (ml)
Upto 50 1.0
51-100 2.0
101-150 3.0
151-200 4.0
201-250 5.0
251-300 6.0
301-350 7.0
351-400 8.0
401-500 9.0
501-550 10.0
ADMINISTRATION
Ivermectin Injection is to be given subcutaneously only. Inject under the loose skin in front of or behind the shoulder. Use of a 17 gauge, half inch (15-20mm) needle is suggested. Replace with a fresh sterile needle after every 10-20 animals. Injection of animals with wet or dirty hides is not recommended.
MODE OF ACTION
Ivermectin paralyses and ultimately kills parasitic nematodes, arachnids and insects by its effect on the nervous system of these parasites. At the therapeutic doses, Ivermectin has no adverse effect on cattle since it does not readily penetrate their central nervous systems. Ivermectin belongs to the avermectin class of anthelmintic endectocides.
WHEN TO USE
The suggested dosing programme has been developed to make the best use of the properties of Ivermectin injection. Your veterinary surgeon will be able to provide further advice.
Stomach and Gut Roundworms
Roundworms larvae may survive on the pasture over the winter in great numbers. They infect grazing cattle immediately after turnout, maturing into egg laying worms and causing increased pasture contamination. Early season treatment with Ivermectin injection keeps down the population of worms in your stock and reduces the number of worm eggs passed onto the pasture to cause later infection.
Where young cattle are set-stocked, treatments with Ivermectin Injection 3, 8 and 13 weeks after an April / May turn-out will give season long control of parasitic gastro-enteritis and parasitic bronchitis.
PRECAUTIONS
Transitory discomfort has been observed in some cattle following subcutaneous administration. Tissue swellings at the injection site have been observed. These reactions resolve without treatment. Further information is available upon request.
Do not smoke or eat while handling the product. Wash hands after use.
SIDE- EFFECTS
Symptoms of poisoning in cattle include general motor depression, increased respiratory rates, muscle fasciculations, mydriasis and extensor rigidity of the limbs.
In cases of suspected overdosage, symptomatic and supportive therapy should be given as appropriate.
NOTE TO USER
Take care to avoid self-administration: Transitory discomfort has been observed in some cattle following subcutaneous administration. Tissue swellings at the injection site have been observed. These reactions resolve without treatment.
Ivermectin belongs to the avermectin [3-AV] class of anthelmintic in the endectocides. Chemical group of anthelmintic endectocides [3-AV]
STORAGE
In a cool dry place under 25 centi-degree, away from light.
PACKING
In a 50ml or 100ml glass bottle.
