DESCRIPTION:
White to faintly yellow powder to which appropriate amounts of water are added to prepare an off-white suspension for intramuscular use or a yellow solution for intravenous administration.
SPECIFICATION:
Cefuroxime Sodium for Injection contains either 250mg, 750mg, or 1.5g of cefuroxime. Each 750mg vial contains 42mg sodium (1.8mEq).
INDICATIONS:
A bactericidal cephalosporin antibiotic which is resistant to most β-lactamases and is active against a wide range of Gram-positive and Gram-negative organisms. It is indicated for the treatment of infections before the infecting organism has been identified or when caused by sensitive bacteria.
ADMINISTRATION:
For intravenous and/or intramuscular administration.
DOSAGE:
Adults
Many infections respond to 750mg three times daily by im or iv injection. For more severe infections the dose should be increased to 1.5g three times daily iv. The frequency of administration may be increased to 6-hourly if necessary, giving total daily doses of 3 to 6g.
Infants and Children
30 - 100mg/kg/day given as 3 or 4 divided doses. A dose of 60mg/kg/day is appropriate for most infections.
CONTRAINDICATIONS:
Hypersensitivity to cephalosporin antibiotics.
SIDE EFFECTS
Occurred relatively infrequently and have been generally mild and transient in nature.
SHELF LIFE
36 months at 25°C, protected from light.
Suspensions of Cefuroxime Sodium for Injection for intramuscular injection and aqueous solutions for direct intravenous injection retain their potency for 24 hours if refrigerated.
PACKAGE
Vials containing 250mg, 750mg and 1.5 g cefuroxime as the sodium salt in packs of 10.
