Pioneers Group

Penicillin G procaine (also known as APPG, Aqueous Procaine Penicillin G , Benzylpenicillin Procaine, Procaine Penicillin G, Procaine Benzylpenicillin) is the pro­caine monohydrate salt of penicillin G. In vivo it is hydrolyzed to penicillin G and acts as a depot, or repository form of penicillin G. It occurs as white crystals or very fine, white crystalline powder. Approximately 4-4.5 mg are soluble in 1 ml of water and 3.3 mg are soluble in 1 ml of alcohol. Potency of Penicillin G procaine is usually expressed in terms of Units. One mg of Penicillin G procaine is equivalent to 900-1050 USP Units. The commercially available suspension for injection is buffered with sodium citrate and has a pH of 5-7.5. It is preserved with methylparaben and propylparaben.

  

 

Source:pioneer group